GDF3 Protéine

N° du produit ABIN935382

Cette protéine Recombinant GDF3 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour GDF3 Protéine (ABIN935382)

Antigène: GDF3 (Growth Differentiation Factor 3 (GDF3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 98 % pure

Détail du produit

Séquence: AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG

Attributs du produit: Purified recombinant Human GDF3 protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/mL.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

Buffer: Supplied lyophilized with no additives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: GDF3 (Growth Differentiation Factor 3 (GDF3))

Autre désignation: GDF3

Sujet: GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.
Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3

Poids moléculaire: 26 kDa